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Found 3 matching student topics

Displaying 1–3 of 3 results

Novel therapeutic strategies to treat advanced colorectal cancer

Colorectal cancer is a very common disease, with over 15,000 new cases diagnosed in Australia annually. Metastatic colorectal cancer describes advanced disease that has spread beyond the primary site. This is very aggressive and incurable in the vast majority of these patients. To improve outcomes for colorectal cancer, we are using cutting edge genomic and cell biology techniques to understand disease heterogeneity and optimise drug response. We are developing novel therapeutic interventions based on unique molecular signatures and are testing …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Using systems architecture to model neuropathic pain

Neuropathic pain effects '1 in every 10 adults over the age of 30'. The treatments available for neuropathic pain can at best be described as having 'moderate efficacy'. Due to the nature of neuropathic pain, the ability to scientifically study and understand its fundamental causes has been limited to animal models and trials. There are over 27 animal models for neuropathic pain where pain has been induced by macroscopic and microscopic nerve lesions, chemotherapy, viral infections and diabetes mellitus.Looking at …

Study level
PhD
School
School of Mechanical, Medical and Process Engineering

Mathematical modelling of ecosystem feedbacks and value-of-information theory

Ecosystems respond to gradual change in unexpected ways. Feedback processes between different parts of an environment can perpetuate ecosystem collapse, leading to potentially irreversible biodiversity loss. However, it is unclear if greater knowledge of feedbacks will ultimately change environmental decisions.The project aims to identify when feedbacks matter for environmental decisions, by generating new methods that predict the economic benefit of knowing more about feedbacks. Combining ecological modelling and value-of-information theory, the outcomes of these novel methods will provide significant and …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science
Centre for the Environment

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